See Also: aplastic anemia(encyclopedia)
Aplastic anemia(health)
Anemia, aplastic(health)
aplastic(medicine)
aplastic anaemia(medicine)
aplastic lymph(medicine)
anaemia, aplastic(medicine)
congenital aplastic anaemia(medicine)
anemia(encyclopedia)
anemia(medicine)

Amplification (health) and aplastic anemia (sh)


Amplification (health)


"Making multiple copies of a gene or of any sequence of DNA. Repeated copying of a piece of DNA. In amplification there is an increase in the number of copies of any particular piece of DNA. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally ""in glass"", or in a plastic vessel in the laboratory). "





aplastic anemia (sh)




or anemia of bone-marrow failure

Inadequate blood-cell formation by bone marrow.

Pancytopenia is the lack of all blood-cell types (erythrocytes, leukocytes, and platelets), but any combination may be missing. Drug, chemical, or radiation exposure most often causes the disease, but about half of all cases have no known cause. It may occur at any age. Acute disease may be quickly severe, even fatal; chronic disease has symptoms including weakness, shortness of breath, headache, fever, and pounding heart. There is usually a waxy pallor. Hemorrhages occur in mucous membranes, skin, and Other organs. Lack of white blood cells lowers resistance to infection and becomes the major cause of death. Very low platelet count may lead to severe bleeding. The treatment of choice is bone-marrow transplantation. Otherwise treatment involves avoiding any known toxic agent and giving fluids, glucose, and proteins (often intravenously) as well as blood components and antibiotics.