See Also: Attenuated familial adenomatous polyposis(health)
Familial adenomatous polyposis(health)
familial adenomatous polyposis(medicine)
adenomatous polyposis coli(medicine)
Adenomatous polyposis coli(health)
Colorectal adenomatous polyposis, recessive(health)
Adenomatous polyposis coli, autosomal recessive(health)
familial polyposis(medicine)
Familial polyposis(health)
familial polyposis coli(medicine)

Attenuated familial adenomatous polyposis (health)


An inherited predisposition to colorectal cancer characterized by fewer than 100 adenomatous polyps in the colon and rectum. It is said to be attenuated because there are fewer polyps than in classic familial adenomatous polyposis (FAP). People with attenuated familial adenomatous polyposis (AFAP) also tend to be older at the diagnosis of their polyps (average age of 44 years) and cancer (average age of 56 years), 10 to 15 years later than in classic FAP. The right side of the colon tends to be involved in AFAP and rectal involvement is rare. AFAP is transmitted in an autosomal dominant manner.