See Also: 3-iodobenzylguanidine(medicine)
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3-iodobenzylguanidine (medicine)


3-iodobenzylguanidine
<chemical> A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumours. The radiolabelled forms are used as antineoplastic agent and radioactive imaging agents. (merck index, 12th ed) mibg serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.

Pharmacological action: antineoplastic agent, enzyme inhibitors, radiopharmaceuticals, sympatholytics.