See Also: 5-pyrrolidone-2-carboxylic acid(medicine)
pyrrolidone(dictionary)
pyrrolidone(medicine)
pyrrolidone-5-carboxylate(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Consanguinity(law)
consanguinity(dictionary)
Consanguinity(medicine)
consanguinity(dictionary)
Consanguinity(health)

5-pyrrolidone-2-carboxylic acid (medicine) and Consanguinity (health)


5-pyrrolidone-2-carboxylic acid (medicine)


5-pyrrolidone-2-carboxylic acid -->
5-oxoproline


A keto derivative of proline that is formed nonenzymatically from glutamate, glutamine, and gamma-glutamylated peptides; it is also produced by the action of gamma-glutamylcyclotransferase; elevated levels of 5-oxoproline are often associated with problems of glutamine or glutathione metabolism.

Synonym: 5-pyrrolidone-2-carboxylic acid, pyroglutamic acid, pyrrolidone-5-carboxylate.


Consanguinity (health)


Having a common ancestor, ie, being blood relatives. Mating between two first cousins, for example, can be termed a consanguineous mating and is indicated in a pedigree by a double bar between the two parents. Such mating can result in an increased frequency of offspring who are *homozygous* for a recessive autosomal trait possessed by both parents, eg cystic fibrosis.