See Also: Acute monocytic leukaemia(medicine)
monocytic leukaemia(medicine)
Schilling type of monocytic leukaemia(medicine)
Naegeli type of monocytic leukaemia(medicine)
Acute leukaemia(medicine)
leukaemia, erythroblastic, acute(medicine)
Acute lymphocytic leukaemia(medicine)
Acute myeloid leukaemia(medicine)
leukaemia, myelocytic, acute(medicine)
acute myelogenous leukaemia(medicine)

Acute monocytic leukaemia (medicine)


acute monocytic leukaemia
<haematology> The most common translocation in this disorder of poorly differentiated monocytic cells involves chromosome region 11q in a large percentage of cases.

The translocation involves a cellular oncogene, c-ets which is mapped to the 11q23-24 region. The most common translocations reported are t(6;11), t(9;11), t(11;17) and t(11;19), of which t(9;11) (p21-22;q23) is by far the most frequently detected and implicated in acute myeloid leukaemia. The cells express CD14 surface antigen, which is diagnostic of monocytic cells.

Acronym: AML

Classification: FAB M5