See Also: Beta-hydroxy-beta-methylglutaryl-CoA(medicine)
3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase(medicine)
3-Hydroxy-3-methylglutaryl-CoA(medicine)
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferase(medicine)
beta-1,3-galactosyl-0-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase(medicine)
beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase(medicine)
UDP-GalNAc-beta-galactose beta 1,4-N-acetylgalactosaminyltransferase(medicine)
androst-5-ene-3 beta,17 beta-diol(medicine)
beta-n-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase(medicine)
5 alpha-androstane 3 beta,17 beta-diol 7 alpha-hydroxylase(medicine)

Beta-hydroxy-beta-methylglutaryl-CoA (medicine)


beta-hydroxy-beta-methylglutaryl-CoA


-OOCCH2C(OH)(CH3)CH2COS-CoA;a key intermediate in the synthesis of ketone bodies and of steroids.

Synonym: 3-hydroxy-3-methylglutaryl-CoA.

Beta-hydroxy-beta-methylglutaryl-lyase, an enzyme, found primarily in liver and rumen epithelium that catalyses the formation of acetyl-CoA and acetoacetate from beta-hydroxy-beta-methylglutaryl-CoA; a key step in ketogenesis; a deficiency of this enzyme leads to episodes of severe metabolic acidosis without ketosis.

Beta-hydroxy-beta-methylglutaryl-reductase, an enzyme that catalyses the rate-limiting step of cholesterol biosynthesis, beta-hydroxy-beta-methylglutaryl-CoA + 2NADPH + 2H+ → mevalonate + 2NADP+ + coenzyme A.

Beta-hydroxy-beta-methylglutaryl-synthase, an enzyme in mitochondria that catalyses the reaction of acetyl-CoA with acetoacetyl-CoA and water to form beta-hydroxy-beta-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur.