See Also: Donath-Landsteiner cold autoantibody(medicine)
Donath-landsteiner(medicine)
Donath-Landsteiner phenomenon(medicine)
Landsteiner-Donath test(medicine)
cold autoantibody(medicine)
haemagglutinating cold autoantibody(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Donath, Julius(medicine)
autoantibody(medicine)
Landsteiner(medicine)

Donath-Landsteiner cold autoantibody (medicine)


Donath-Landsteiner cold autoantibody


An autoantibody of the IgG class responsible for paroxysmal cold haemoglobinuria; it is adsorbed to red cells only at temperatures of 20°C or lower, causing the red cells to lyse in the presence of complement at higher temperatures; it has only slight agglutinating properties in spite of its marked lytic activity, and has a specificity within the blood group P; it is also occasionally present for short periods of time following measles and other infections, and formerly was frequently associated with syphilis.

Synonym: cold haemolysin.