See Also: Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
aflatoxin(encyclopedia)
Aflatoxin(health)
aflatoxin(medicine)
aflatoxin(dictionary)
aflatoxin m1(medicine)
aflatoxin b1(medicine)
aflatoxin G2a reductase(medicine)
aflatoxin B1 reductase(medicine)
aflatoxin B1 hydroxylase(medicine)

aflatoxin b1 (medicine)


aflatoxin b1
<chemical> A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals.

It is found as a contaminant in peanuts, cotton seed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin b1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin m1 and q1.

Pharmacological action: carcinogens, mutagens, teratogens.

Chemical name: Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-