See Also: Enchiladas with Mole Poblano(recipes)
chimeric-2fhumanised antibody(medicine)
Pumpkin enchiladas with mole sauce(recipes)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
poblano(dictionary)
Chimeric(medicine)
chimeric DNA(medicine)
chimeric proteins(medicine)
chimeric molecule(medicine)
chimeric antibodies(medicine)
chimeric-2fhumanised antibody (medicine) and Enchiladas with Mole Poblano (recipes)
chimeric-2fhumanised antibody (medicine)
chimeric/humanised antibody
<immunology> Genetically engineered combination of a human and mouse antibody. Because a monoclonal antibody is always made with mice cells, it causes an immune response when injected into humans.
By replacing the constant regions of a mouse antibody with those of a human antibody, an antibody that binds to an antigen like the original monoclonal antibody, but which is recognised by the human immune system like a human protein, can be manufactured. Alternatively, only those amino acids directly involved in antigen binding are transferred from the mouse antibody into the framework of the human antibody, with a similar result.
Enchiladas with Mole Poblano (recipes)
Makes 8-10 enchiladas
1 jar of Rancho la California mole sauce
2-4 cups of chicken stock (recipe follows)
2 cups shredded chicken
½ onion, diced
1 garlic clove, minced
2 Tablespoons vegetable oil
¼ cup sesame seeds, toasted
Preheat oven to 375 degrees
Making the Mole
This step can be done a day or so in advance.
Pour jar of mole sauce into large sauté pan and heat over low heat. Add chicken stock one cup at a time. Stir each cup of stock into sauce until it is totally incorporated. Keep adding stock and stirring for approximately ½ hour. During this time, remove any fat (it will be dark brown) and reserve in a bowl. You should have approximately ¼ to ½ cup of fat.
The mole and fat will keep in the refrigerator for up to 2 days. You can use the mole over chicken breasts or thighs, sprinkled with toasted sesame seeds.
Preparing the Enchiladas
Lightly grease the Baking pan.
Sauté the onion and garlic quickly in the vegetable oil, remove and set aside.
Next, get your workspace set up. Put the shredded chicken in one bowl, next to the bowl with the onion and garlic. Have the tortillas ready, next to the stove, and a rectangular Baking dish ready.
Pour the fat from the mole sauce into a small skillet and heat over medium heat. Using tongs, dip the tortillas into the fat until lightly covered. With the hot tortilla flat on a plate, add 1 tablespoon of chicken at one end. Then top with 1 tablespoon of the onion/garlic mixture. Roll up the tortilla from the filled end and place in the Baking pan.
Repeat with the remainder of the tortillas. If you run out of fat from the mole, add a bit of vegetable oil.
Bake for approximately 30 minutes.
Before serving, heat the mole over low heat until it is hot. When you are ready to serve, spoon the mole over the tortillas and sprinkle with sesame seeds.
Quick Mexican Chicken Stock
8 Chicken thighs or breasts (with skin and bone)
½ medium onion, chopped
1 – 2 garlic cloves, peeled and sliced
1-2 sprigs cilantro (optional)
6 cups water
Combine all ingredients in a saucepan. Bring to a boil, and then lower to a simmer. Simmer for approximately ½ hour or until chicken is cooked.
You can use this chicken for your Enchiladas or Mole Poblano and the stock is ready to use in your mole.
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