See Also: insulin-like growth factor-binding protein 2(medicine)
insulin-like growth-factor-binding-protein 5(medicine)
insulin-like-growth-factor-binding protein 6(medicine)
insulin-like growth-factor binding protein 1(medicine)
insulin like growth-factor-binding protein 4(medicine)
insulin-like growth factor binding protein 3(medicine)
insulin-like growth-factor-binding proteins(medicine)
heparin binding growth factor(medicine)
insulin like growth factor(medicine)
insulin-like growth factor II(medicine)

insulin-like growth-factor binding protein 1 (medicine)


insulin-like growth-factor binding protein 1


One of the six homologous proteins that specifically bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits igf binding to cell surface receptors and thereby inhibits igf-mediated mitogenic and cell metabolic actions. (proc soc exp biol med 1993;204(1):4-29)