See Also: Langerhans cell(medicine)
langerhans cell histiocytoses(medicine)
histiocytosis, langerhans-cell(medicine)
histiocytosis, non-langerhans-cell(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
langerhans(medicine)
Langerhans(dictionary)
Langerhans' granule(medicine)
Langerhans, islets of(encyclopedia)
islets of Langerhans(medicine)

langerhans cell histiocytoses (medicine) and cottage (oh)


langerhans cell histiocytoses (medicine)


langerhans cell histiocytoses


An immunologic disorder of unknown cause where there is proliferation of histiocytes (a type of cell in the immune system) in the bloodstream. The disorder is characterised by inflammation of the bronchioles and small pulmonary vessels that leads to fibrosis and destruction of alveolar cell walls. Cigarette smoking is considered a risk factor. Individuals with this disorder are also at increased risk for spontaneous pneumothorax.

Symptoms include cough, chest pains, shortness of breath, fever, Weight Loss and malaise. Bronchoscopy with biopsy confirms the diagnosis. Childhood forms exist and cause more systemic symptoms and findings such as failure to thrive, Weight Loss, fevers, irritability, rash and bone pains. Treatment is with corticosteroids.


cottage (oh)



[Date: 1300-1400; Language: Anglo-French; Origin: cotage, from English cot 'cottage', from Old English]
a small house in the country
::a country cottage
::We're staying in a holiday cottage in Dorset.