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methionine synthase (medicine)


methionine synthase


Tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase;an enzyme that catalyses the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities.

Synonym: tetrahydrofolate methyltransferase.