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midkine (medicine)


midkine
<growth factor> Heparin binding growth factor (13 kD) of the TGF superfamily, has 50% sequence identity with Heparin Binding Growth Associated Molecule (HB GAM). Structurally unrelated to FGF. Midkine was originally described as associated with tooth morphogenesis induced by epithelial mesenchyme interactions. Nucleolin binds midkine.