See Also: ping-pong mechanism(medicine)
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Ping-Pong(dictionary)
ping-pong(1)(dictionary)
ping-pong(2)(dictionary)
ping-pong(medicine)
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pong(2)(dictionary)

ping-pong mechanism (medicine)


ping-pong mechanism


A special multisubstrate reaction in which, for a two-substrate, two-product (i.e., bi-bi) system, an enzyme reacts with one substrate to form a product and a modified enzyme, the latter then reacting with a second substrate to form a second, final product, and regenerating the original enzyme. An example of such a mechanism is found in the aminotransferases. More complex ping-pong mechanisms exist for enzymes having more than two substrates.

Synonym: double displacement mechanism.