See Also: receptors, n-methyl-d-aspartate(medicine)
n methyl D aspartate receptor(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Aspartate(medicine)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
IMP-aspartate ligase(medicine)
L-aspartate oxidase(medicine)
aspartate 1-decarboxylase(medicine)
aspartate N-acetyltransferase(medicine)
Aspartate aminotransferase (AST)(health)

receptors, n-methyl-d-aspartate (medicine)


receptors, n-methyl-d-aspartate


A class of ionotropic glutamate receptors characterised by affinity for n-methyl-d-aspartate. Nmda receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.