tartrate-resistant acid phosphatase (medicine)

tartrate-resistant acid phosphatase
<biochemistry, enzyme> Acid phosphatase is present in bone, prostate, platelets, erythrocytes and spleen.

Osteoclasts contain an isoenzyme that is resistant to tartrate, whereas, the isoenzyme in the prostate is sensitive. Tartrate-resistant acid phosphatase is elevated in the serum of patients with primary hypoparathyroidism, Paget disease, vertebral osteoporosis, T-cell lymphoma and in women after oophorectomy. Oestrogen replacement in osteoporotic postmenopausal women is associated with a decrease in tartrate-resistant acid phosphatase of 70% over 3 to 6 months.

Acronym: TRAP

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tartrate-resistant acid phosphatase (medicine)

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