See Also: tetrahydrofolate dehydrogenase(medicine)
5,6,7,8-tetrahydrofolate dehydrogenase(medicine)
methylene tetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
tetrahydrofolate methyltransferase(medicine)
formate-tetrahydrofolate ligase(medicine)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
Orthomolecular medicine (orthomolecular nutritional medicine, orthomolecular therapy)(health)
medicine(encyclopedia)
medicine man(encyclopedia)

tetrahydrofolate dehydrogenase (medicine)


tetrahydrofolate dehydrogenase
<enzyme> An enzyme of the oxidoreductase class that catalyses the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme.

Chemical name: 5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase

Registry number: EC 1.5.1.3